Creatine monohydrate is creatine bound to a water molecule. It is often used by athletes and bodybuilders to improve athletic performance. Creatine is naturally produced by the body and is also consumed. in meat, but adding creatine monohydrate increases the amount found in the body. This particularly affects skeletal muscle, as over 90% of the creatine in the body is found in these muscles. This is mainly because creatine plays an important role in energy supply, and skeletal muscle – especially in a serious athlete – uses a lot of energy. Creatine monohydrate supplements have long been shown to increase creatine in the muscles, making it easier to get the most out of a workout and build lean skeletal muscle.